Anthropometry, Fatty Liver, Plasma Lipid, and Adipose Tissue on Rat Wistar Induced Low-Protein Diet

Authors

  • Dian Handayani Nutrition Department Brawijaya University
  • Inggita Kusumastuty Nutrition department, Brawijaya University
  • Kanthi Permaningtyas Tritisari Nutrition department , Brawijaya University
  • Laily Ekawati
  • Glaveria Galuh
  • Lailatul Muniro
  • Lega Satya
  • Ratih Indah Supratiwi
  • Anis Mahmudah

DOI:

https://doi.org/10.11594/jtls.07.01.08

Keywords:

Protein nergy malnutrition (PEM), low protein diet, anthropometry, fatty liver

Abstract

Protein energy malnutrition problem still exists in developing country. In fact, Indonesia has faced it as double burden of nutrition problems. This study aims to develop a standardized diet for developing protein energy malnutrition (PEM) on the rat to support nutrition research. Low-protein modified AIM-93M diet (LP) has been given to rats for 12 weeks intervention compared to normal protein diet (ND). Anthropometry, plasma lipid, fatty liver and the weight of adipose tissue have been analysed. The LP group showed a significantly lower body weight, body length and waist circumference (p < 0.05), a more fatty liver marker shown in LP compared to ND (p < 0.05). This study suggests that giving low protein modified AIN-M93 diet promotes protein energy malnutrition in the rat.

Author Biographies

Dian Handayani, Nutrition Department Brawijaya University

clinical nutrition

Inggita Kusumastuty, Nutrition department, Brawijaya University

Clinical nutrition

Kanthi Permaningtyas Tritisari, Nutrition department , Brawijaya University

Clinical nutrition

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Published

2017-04-18

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